It was raining, so I walked over to the U. I’ve spent about 30 hours there this week, and my commitment continues in four-week units, depending on the results. At a minimum, I’m helping cancer research, but I’m also hoping to help myself by kicking my daemon further down the road.
Category: Health
Minimizing visits to Urgent Care
Arrived today: silicone food containers. Excruciating pain from a tiny shard of glass embedded in my foot from our old glass set brought me to Urgent Care twice. Although these containers are expensive, I don’t expect them to generate any Urgent Care copays. They’re oven-safe to 450°F, so I’ll just need to watch out for burns instead.
Very nearly an armful of blood*
Got my first dose of the study drug, amB7-H3 TriKE. Here, tubes are lined up for one draw (the second of seven draws) as they monitor me over several hours. All of these are strictly for research, so the results won’t show up in my online medical record. *Inspired by a line from the classic 1961 BBC television episode “The Blood Donor” starring British comedian Tony Hancock.
Helping research, helping myself
Posted “Helping research, helping myself.” Click through for a link. Reflecting on a clinical study I’m starting on Monday got me thinking about Britain’s Common Cold Unit (1946–1990) where people volunteered to get the cold or ‘flu.
Helping research, helping myself
Next week, I begin a Phase 1 trial testing a drug designed to prime my natural killer cells against cancer. As only the third patient in the study, I’ll receive daily injections for two weeks. Reflecting on research volunteers brought to mind Britain’s Common Cold Unit (1946–1990), whose work included isolating coronaviruses and testing interferons, paving the way for modern immune-modulating treatments.
Journey to a bowl of joy
Put on one of my “ramen tees,” which still bears the faint evidence of previous splashes that no amount of washing will completely hide. Then, I headed over to the U for a morning of pokes, stabs, and staying motionless for 25 minutes. Afterward, a bowl of tonkotsu udon took me straight to a happy place where everything is all right.
Intermission
There were no takers for pre-show drinks outside, where it was a sweltering 90-plus degrees, but inside Orchestra Hall, the AC was doing a grand job. Following medical scans this afternoon, with more lined up for Monday, a glass of wine and an escape into the world of Britten, Beethoven, and Schumann were most welcome.
Turbocharging my killer cells
Walked home from the U through smoke after consenting to a Phase 1 clinical trial. If tests over the next week continue to qualify me, I’ll receive a “Tri-Specific Killer Engager” (!) immunotherapy agent that may harness my immune system to kill tumor cells. I’ve been on Phase 2 and 3 trials; this one is more experimental, but I’m hopeful it will kick the can further down the road.
Artificial and real intelligence
Attended a panel discussion on AI in cancer research and care. It’s not the kind of event that would normally catch my eye, but when I received an email from the U about it, I decided to go. My oncologist, a professor at the U who researches recurrent and advanced prostate cancer and uses AI in his work, was one of the featured speakers. Hearing him speak reassured me that his real intelligence and good humor won’t be replaced by a machine anytime soon.
I shall never play the violin
I’m grateful for modern science, and for a comforting bowl of tonkotsu udon a couple blocks from the hospital. My oncologist had just recommended a newly developed test that sequences the evolving DNA of the tumor and white blood cells to point toward new, targeted treatments, including immunotherapy. In old movies, it’s a little doctor in Vienna proclaiming, “You shall play the violin again.” In real life, it’s just science.