Next week, I begin a Phase 1 trial testing a drug designed to prime my natural killer cells against cancer. As only the third patient in the study, I’ll receive daily injections for two weeks. Reflecting on research volunteers brought to mind Britain’s Common Cold Unit (1946–1990), whose work included isolating coronaviruses and testing interferons, paving the way for modern immune-modulating treatments.
Category: Living
A community’s values
After a cycle ride and cuppa with my friend, I made my way through Seward, a neighborhood where it was no surprise every stop sign had been carefully changed to “STOP ICE” and lawns carried community-minded messages. I couldn’t stop myself thinking administration officials must have never read the Beatitudes despite claiming their love of the Bible. “Blessed are those who hunger and thirst for righteousness… Blessed are the peacemakers.”
Mind the gap
It seemed safe enough to ignore the diversion signs while running errands. The 20-year-old Blue Line LRT is closed for seven weeks for major maintenance, including replacing some track and upgrading signals. I sometimes take my bike on the train to reach further-out trailheads, and it’s our go-to route to the airport.
Journey to a bowl of joy
Put on one of my “ramen tees,” which still bears the faint evidence of previous splashes that no amount of washing will completely hide. Then, I headed over to the U for a morning of pokes, stabs, and staying motionless for 25 minutes. Afterward, a bowl of tonkotsu udon took me straight to a happy place where everything is all right.
Breathing unhealthy air
Viewed downtown through smoky air on our usual Sunday morning walk. American and Canadian firefighters are working side-by-side to control blazes in Minnesota’s Boundary Waters, even as the president threatens to impose tariffs on Canada over their forest fire smoke, a power he actually lacks. Meanwhile, the administration is busy rebranding terms like “climate change,” canceling wind farm developments, and promoting the construction of new coal-fired power plants.
Intermission
There were no takers for pre-show drinks outside, where it was a sweltering 90-plus degrees, but inside Orchestra Hall, the AC was doing a grand job. Following medical scans this afternoon, with more lined up for Monday, a glass of wine and an escape into the world of Britten, Beethoven, and Schumann were most welcome.
Turbocharging my killer cells
Walked home from the U through smoke after consenting to a Phase 1 clinical trial. If tests over the next week continue to qualify me, I’ll receive a “Tri-Specific Killer Engager” (!) immunotherapy agent that may harness my immune system to kill tumor cells. I’ve been on Phase 2 and 3 trials; this one is more experimental, but I’m hopeful it will kick the can further down the road.
Eliminating trial and error with a dynamic breaker map
Mapped circuit breakers to outlets, appliances, and lights on a floor plan, then added a QR code to the breaker box linking to it. There are a few orphan outlets left to figure out, but adding them to the digital plan later means I won’t need to update the physical QR code.
Topping off the tanks at Duluth Junction
Cycled home from Stillwater. At Duluth Junction, a nod to the rail trails we were riding, we stopped for a water break. There, we had a nice chat with our photographer: a woman who lives in a seniors’ building and was out for her daily 15-miler.
Cycle to Stillwater for the night
Cycled to Stillwater, off-road trails all the way, taking about four hours. It was scorching hot, but the trails were often shaded, and we cooled off at lunch in a dark dive bar. We’re spending the night in Stillwater, then heading home tomorrow. Here, we’re taking an after-dinner stroll, about to cross the St. Croix River, looking toward Wisconsin.